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A biweekly newsletter on evidence in Digital Health startups.
By ProofStack.Health
Proof Points
Paul Wicks
Paul Wicks

I help digital health companies plan and publish peer-reviewed evidence 10x faster

L3 Proof Points: I was rejected six times (how "move fast and prove things" got started)

Sep 24, 2026

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6 min read

L3 Proof Points: I was rejected six times (how "move fast and prove things" got started)

My first paper took seven years, here's how we get it under seven months.

Paul Wicks
Paul Wicks
L2 Analysis: The most mocked sentence in American politics is (now) a data framework

Sep 10, 2026

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8 min read

L2 Analysis: The most mocked sentence in American politics is (now) a data framework

The three questions to ask before you run a single analysis.

Paul Wicks
Paul Wicks
L1 Data: Data is not the new oil. So what is it?

Aug 27, 2026

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7 min read

L1 Data: Data is not the new oil. So what is it?

Your investors told you to collect it. Most of it will never be analysed.

Paul Wicks
Paul Wicks

Evidence Stack

L0 Governance: Do you know the rules of the evidence game?

Aug 13, 2026

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5 min read

L0 Governance: Do you know the rules of the evidence game?

Three real cases where weak governance nearly destroyed a good paper.

Paul Wicks
Paul Wicks
What is your evidence worth? The price tag on a P-Value

Jul 30, 2026

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3 min read

What is your evidence worth? The price tag on a P-Value

Evidence and enterprise value (while I'm off in the Canaries)

Paul Wicks
Paul Wicks
Don't tweet to your critics. Do this instead.

Jul 16, 2026

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6 min read

Don't tweet to your critics. Do this instead.

OpenEvidence lost to Nature Medicine. Then it lost the plot on X.

Paul Wicks
Paul Wicks
Guess who got kicked out of HLTH Europe?

Jul 2, 2026

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4 min read

Guess who got kicked out of HLTH Europe?

A skincare booth broke the rules at HLTH Europe. Security didn't hesitate.

Paul Wicks
Paul Wicks
What happens when a competitor calls your baby ugly?

Jun 18, 2026

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5 min read

What happens when a competitor calls your baby ugly?

A guide to scientific crisis management... best written before you need it.

Paul Wicks
Paul Wicks
Red teaming your mental health AI (before critics do)

Jun 4, 2026

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5 min read

Red teaming your mental health AI (before critics do)

How to Launch an AI Mental Health App... and not pull it from the App store.

Paul Wicks
Paul Wicks
Are the goblins among us in healthcare?

May 21, 2026

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4 min read

Are the goblins among us in healthcare?

1 in 277 papers now contain fabricated citations. We can't tell them apart.

Paul Wicks
Paul Wicks

Clinical Trials

I've helped design clinical trials for 15 years. Then I participated in one.

May 7, 2026

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7 min read

I've helped design clinical trials for 15 years. Then I participated in one.

What 3 months of flavour-changing chewing gum taught me about evidence.

Paul Wicks
Paul Wicks

AI

Your ChatGPT just diagnosed you (but it's a fake disease)

Apr 23, 2026

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6 min read

Your ChatGPT just diagnosed you (but it's a fake disease)

Bixonomania doesn't exist. ChatGPT diagnosed it anyway. Here's why that matters for your evidence strategy.

Paul Wicks
Paul Wicks
What does an “Evidence Engine” actually look like?

Apr 9, 2026

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5 min read

What does an “Evidence Engine” actually look like?

How a Portuguese hospital embarrassed every ChatGPT benchmark in existence

Paul Wicks
Paul Wicks
The internet was once a fad. Now it's in Nature Medicine.

Mar 26, 2026

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4 min read

The internet was once a fad. Now it's in Nature Medicine.

The journals that rejected this field for 20 years are now chasing it.

Paul Wicks
Paul Wicks

AI

HIMSS, AI Hype, and the paper that OpenAI did not want written

Mar 19, 2026

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5 min read

HIMSS, AI Hype, and the paper that OpenAI did not want written

40 Million Health conversations per day. Zero peer review. We have a problem.

Paul Wicks
Paul Wicks
Digital health is a gamble. But where's the evidence? 🎰

Feb 26, 2026

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6 min read

Digital health is a gamble. But where's the evidence? 🎰

PLUS: Our podcast just launched, HIMSS is looming, and we may throw a secret party.

Paul Wicks
Paul Wicks

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Proof Points

A Newsletter by ProofStack.Health

Extraordinary claims require extraordinary evidence.

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