
Biweekly frameworks, case studies, and hard-won lessons from a neuropsychologist who has published 200+ studies and reviewed thousands more. Written for digital health founders who want to make bold claims—and back them up.
peer-reviewed publications
clients achieved publications*
editorial boards incl The BMJ

Extraordinary claims require extraordinary evidence — but startup operators don’t have time to navigate the complexity of peer-reviewed publishing. ProofStack helps you understand where you stand, define what’s missing, and build a strategic evidence roadmap that turns science into traction.
Who is this newsletter for?
MedTech Founders, Chief Medical Officers, and Investors in Digital Health Companies.
What is this newsletter about?
We share biweekly frameworks, case studies, and cautionary tales that help digital health companies prove their products actually work.
Will it help my company raise or sell better?
We won’t make any promises, but we’d like to believe so. The focus of every newsletter is on the kind of evidence investors, payers, clinicians, and regulators actually look for, and how to build it without wasting years.
What's the story behind Proof Points?
We believe extraordinary claims require extraordinary evidence (yes, we are quoting the Carl Sagan). With over 25 years of publishing clinical research, we’ve seen too many MedTech startups burn through capital and lose traction in their product because they did not ‘prove it.’ This newsletter is an homage to the MedTech companies seeking capital and peace of mind.
Paul is a PhD neuropsychologist and expert in digital health, clinical trials, and patient centricity. For over 13 years he worked as R&D Director and VP of Innovation at PatientsLikeMe, an online community for over 850,000 people living with medical conditions. Paul is featured in over 9,000+ Google Scholar citations and has published over 200 studies including a patient-driven observational trial of lithium in ALS, numerous patient-reported outcome measures, a “dose-response” curve for the benefits of friendship between patients, and methods for patient-centered and virtual clinical trial designs.
His work has been featured by the BBC, NPR, CNN, The Wall Street Journal, and The New York Times.Former editorial board member of The BMJ, BMC Medicine, JMIR, and more.
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Conversations at the intersection of digital health, clinical evidence, and scientific credibility. We explore how founders, medical leaders, and researchers turn rigorous science into real-world traction.
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